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Verkman CONTENTS Introduction Aquaporin Structure and Transport Function Aquaporin Expression in Ocular TissuesIndirect Evidence for a Role in Eye Physiology Roles of Aquaporins in Mammalian Physiology Deduced from Phenotypes of AQP-null Mice Ocular Roles of Aquaporins Outside of the Cornea Roles of Aquaporins in the Cornea Summary and Perspective Acknowledgments References INTRODUCTION The eye contains specialized avascular tissues for corneal and lens transparency, secretory epithelia for regulation of aqueous fluid volume and pressure, and electri- cally excitable cells for retinal signal transduction.
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